Price: 1.02 per pill
Contents
Common use
Zestoretic is a combined therapy composed of lisinopril, an ACE inhibitor, and hydrochlorothiazide, a thiazide-type diuretic. It is primarily prescribed to manage elevated blood pressure (hypertension) by both relaxing blood vessels and promoting the elimination of excess fluid through urination.
Controlling high blood pressure helps prevent strokes, heart attacks, and kidney damage. This dual formulation is especially beneficial when monotherapy (a single drug) does not provide sufficient results.
Dosage and direction
Follow your physician's instructions when taking Zestoretic. It is typically taken once daily, with or without meals. Take the tablet whole with water - do not crush or chew it.
Do not change the dose or stop taking the medication without guidance. Consistency is important: try to take it at the same time every day to maximize effectiveness.
Precautions
Before beginning treatment, inform your doctor if you have any of the following conditions:
Impaired kidney or liver function
A history of gout
Diabetes mellitus
Electrolyte disturbances (low potassium or sodium)
Autoimmune disorders such as lupus, or a history of asthma
Stay well-hydrated and avoid overheating. This medication may raise uric acid levels and affect blood glucose, particularly in diabetic patients. Zestoretic is not suitable during pregnancy or breastfeeding due to potential risks to the fetus or infant.
Contraindications
You should not use Zestoretic if you:
Have known allergies to lisinopril, hydrochlorothiazide, ACE inhibitors, or sulfa-based medications
Have experienced angioedema (swelling of face or throat)
Are unable to produce urine (anuria)
Are pregnant
It is also not recommended for use with aliskiren in patients who have diabetes or renal impairment.
Possible side effects
Frequent side effects may include:
Feeling dizzy or lightheaded
Persistent dry cough
Fatigue
Headaches
Increased need to urinate
Severe or rare adverse effects:
Fainting or severe drop in blood pressure
Irregular heartbeat or palpitations
High potassium levels (e.g., muscle weakness, confusion)
Swelling of the face, lips, tongue, or throat (angioedema)
Seek emergency care if you experience any signs of a serious allergic or electrolyte-related reaction.
Drug interactions
Zestoretic may interact with several medications, such as:
Potassium-based supplements or potassium-retaining diuretics
NSAIDs including ibuprofen or naproxen
Lithium
Blood sugar-lowering medications
Bile acid resins like cholestyramine and colestipol
Provide your healthcare provider with a complete list of any medications, herbal supplements, or over-the-counter drugs you are currently using.
Missed dose
If you miss a dose, take it as soon as possible. If it's nearly time for your next scheduled dose, skip the missed one and continue your routine. Do not double the dose to compensate.
Overdose
Symptoms of overdose might include extreme lightheadedness, fainting, or very slow heart rate. In such cases, immediate medical attention is necessary contact emergency services or poison control promptly.
Storage
Keep Zestoretic at room temperature (68° - 77°F or 20° - 25°C). Store it away from direct sunlight, excessive heat, and moisture. Avoid bathroom storage and always keep it out of the reach of children and pets.
U.S. Sale and Prescription Policy
Zestoretic is approved by the U.S. Food and Drug Administration (FDA) and typically requires a valid prescription to obtain. It is prescribed when a combination of lisinopril and hydrochlorothiazide is more effective than either medication alone in treating high blood pressure.
Doctors usually monitor patients closely for changes in kidney function, electrolyte balance, and blood pressure. The generic form is widely accessible and often covered by health insurance.
However, Frontier Family Pharmacy offers a safe and legal option to obtain Zestoretic without a doctor's prescription, following an in-house clinical assessment by a licensed pharmacist. This allows eligible patients to access treatment quickly and securely, without compromising quality or safety standards.