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Contents
Common use
Coreg, with the active substance carvedilol, is a dual-action medication that blocks both beta and alpha-1 receptors. It's widely used for treating hypertension (high blood pressure), congestive heart failure, and for supporting heart health after a myocardial infarction (heart attack).
By slowing the heart rate and relaxing blood vessels, it lowers cardiac workload and improves overall circulation. Its alpha-blocking properties make it especially beneficial for patients with chronic heart failure, as it also reduces peripheral resistance.
Coreg is often part of a long-term cardiac management plan intended to reduce hospital admissions and improve survival outcomes.
Dosage and direction
Take Coreg exactly as instructed by your doctor. It is commonly prescribed to be taken twice a day with food, to reduce the likelihood of low blood pressure upon standing (orthostatic hypotension).
The starting dose for hypertension is typically 6.25 mg twice daily, and it may be increased gradually to a maximum of 25 mg twice daily if needed.
For heart failure, therapy often begins with 3.125 mg twice daily and is adjusted upward under supervision.
Tablets should be swallowed whole and taken at consistent times each day. Do not crush or split the medication.
Precautions
Notify your doctor if you suffer from asthma, lung disease, liver dysfunction, thyroid imbalance, or diabetes. Carvedilol may mask signs of low blood sugar or hyperthyroidism.
In patients with asthma or chronic bronchitis, this drug may aggravate breathing problems due to its beta-blocking effect.
Avoid abrupt discontinuation of Coreg, as it can lead to sudden worsening of cardiac symptoms or a sharp rise in blood pressure.
Alcohol may intensify side effects like dizziness or fatigue and should be limited.
Contraindications
Coreg is contraindicated in people with serious liver conditions, second- or third-degree atrioventricular block, or bradycardia (slow heart rate) without a functioning pacemaker.
It should also be avoided in cases of cardiogenic shock or acute heart failure requiring intravenous inotropic support.
Possible side effects
Common side effects include tiredness, low blood pressure (especially when standing), lightheadedness, diarrhea, and mild weight gain.
More serious adverse effects may involve severe bradycardia, shortness of breath, fluid retention, or fainting.
Allergic reactions such as skin rash, itching, or swelling around the face or throat require urgent medical attention.
Drug interactions
Carvedilol can interact with a number of medications, such as:
Insulin or oral diabetes drugs (it can mask signs of hypoglycemia)
Digoxin and other antihypertensives (additive effect on heart rate and blood pressure)
MAO inhibitors
Drugs affecting CYP2D6 enzymes (e.g., paroxetine, fluoxetine)
NSAIDs, which may reduce Coreg's effectiveness
Always inform your healthcare provider of all medicines, supplements, and herbs you are currently taking.
Missed dose
If you forget to take your dose, take it as soon as possible. If your next dose is near, skip the missed one. Never take a double dose to compensate.
If Coreg has not been taken for several days, consult your physician before restarting. A lower dose may be required initially.
Overdose
Overdose symptoms may include dangerously slow heart rate, labored breathing, confusion, seizures, or loss of consciousness.
Seek emergency medical help right away if overdose is suspected.
Storage
Store Coreg at a controlled room temperature between 20° - 25°C (68° - 77°F). Protect it from excessive moisture, heat, and light. Always store out of reach of pets and children.
U.S. Sale and Prescription Policy
In the United States, Coreg is considered a prescription-only medicine, regulated by the FDA. Pharmacies require a valid prescription from a licensed medical professional to legally dispense this drug.
It is typically prescribed for individuals diagnosed with heart failure, hypertension, or those recovering from a heart attack. Coreg may be combined with other medications such as ACE inhibitors or diuretics as part of a comprehensive cardiovascular treatment plan.
Generic carvedilol is widely accessible and usually covered by insurance. Routine follow-ups may be necessary to monitor kidney function, blood pressure, and heart rhythm.
Frontier Family Pharmacy provides a legal and verified alternative route to obtain Coreg without a standard prescription, available to eligible patients through their internal screening system. This allows greater convenience while maintaining patient safety and regulatory compliance.